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Merck
CN
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主要文件

512731

Millipore

Paromomycin Sulfate

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity.

别名:

Paromomycin Sulfate, Neomycin E

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About This Item

经验公式(希尔记法):
C23H45N5O14 · xH2SO4
CAS号:
分子量:
615.63 (free base basis)
UNSPSC代码:
12352200

质量水平

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

off-white

溶解性

water: soluble

运输

ambient

储存温度

10-30°C

InChI

1S/C23H45N5O14.H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18?,19-,20-,21-,22-,23?;/m1./s1

InChI key

LJRDOKAZOAKLDU-UMIPPVEZSA-N

一般描述

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates paromomycin binding to the A-site of 16S rRNA induces a local conformational change that suggests a mechanism for aminoglycoside action on protein translation.
An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates that paromomycin binding to the A-site of 16S rRNA induces a local conformational change, suggesting a mechanism for aminoglycoside action on protein translation. Also exhibits anti-protozoal properties.
Potency: ≥675 µg/mg.

警告

Toxicity: Harmful (C)

其他说明

VanLoock, M.S., et al. 1999. J. Mol. Biol. 285, 2069.
Blanchard, S.C., et al. 1998. Biochemistry 37, 7716.
Fourmy, D., et al. 1998. J. Mol. Biol. 277, 333.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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