推荐产品
方案
≥98% (HPLC)
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
储存温度
2-8°C
SMILES字符串
[S](=O)(=O)(N)Cc1n[o]c2c1cccc2
InChI
1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)
InChI key
UBQNRHZMVUUOMG-UHFFFAOYSA-N
一般描述
A benzisoxazole derivative that acts as an antiepileptic agent and is shown to block voltage-dependent Na(+) channels and T-type Ca(2+) channels. However, it does not serve as anticonvulsant agent in chemically induced seizures in flurothyl and pentetrazole models. Acts as an inhibitor of monoamine oxidase B (MAO-B; IC50 = 24.8 µM). Displays neurprotective properties.
A benzisoxazole derivative that acts as an antiepileptic agent and is shown to block voltage-dependent Na(+) channels and T-type Ca(2+) channels. However, it does not serve as anticonvulsant agent in chemically induced seizures in flurothyl and pentetrazole models. Acts as an inhibitor of monoamine oxidase B (MAO-B; IC50 = 24.8 µM). Displays neurprotective properties.
Please note that the molecular weight for this compound is batch-specific due to variable water content.
Please note that the molecular weight for this compound is batch-specific due to variable water content.
生化/生理作用
Primary Target
Na+ and Ca2+ channels
Na+ and Ca2+ channels
警告
Toxicity: Harmful (C)
其他说明
Sonsalla, P.K., et al. 2010. Exp. Neurol.221, 329.
Sobieszek, G. et al. 2003. Pol. J. Pharmacol.55, 68.
Sobieszek, G. et al. 2003. Pol. J. Pharmacol.55, 68.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Repr. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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