5.08017
nor-Binaltorphimine Dihydrochloride
≥98% (HPLC), solid, κ-opioid receptor antagonist, Calbiochem
别名:
nor-Binaltorphimine Dihydrochloride, Norbinaltorphimine, nor-BNI, κ Opioid Receptor Antagonist, nor-Binaltorphimine
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关于此项目
经验公式（希尔记法）:
C40H43N3O6 · 2HCl
化学文摘社编号:
分子量:
734.71
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
产品名称
nor-Binaltorphimine Dihydrochloride,
SMILES string
N21CC3(C4(C(Oc%12c4c(ccc%12O)CC2C%13CC%13)c5[nH]c6c(c5C3)CC7(C98C6Oc%10c9c(ccc%10O)CC(N(C7)CC8)C%11CC%11)O)CC1)O
InChI
1S/C40H43N3O6/c44-27-7-5-21-13-25(19-1-2-19)42-11-9-39-29(21)33(27)48-35(39)31-23(15-37(39,46)17-42)24-16-38(47)18-43-12-10-40(38)30-22(14-26(43)20-3-4-20)6-8-28(45)34(30)49-36(40)32(24)41-31/h5-8,19-20,25-26,35-36,41,44-47H,1-4,9-18H2
InChI key
GYEXSFKLGQBRBJ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
white to off-white
solubility
water: 50 mM
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Primary Target
kappa opioid receptor
kappa opioid receptor
Disclaimer
Toxicity: Standard Handling (A)
General description
A potent antagonist highly selective for κ opioid receptor with no effect on µ- or &delta- opioid receptors. Widely used in studies related to pain, addition, anxiety, depression, and sleep.
Other Notes
Kishioka, S., et al. 2013. Neurosci. Letters.In press.
Valdez, G., et al. 2012. Pharma. Biochem. and Behavior.102, 44.
Takemori AE et al. 1988. J. Pharmacol. Exp. Ther.246, 255.
Valdez, G., et al. 2012. Pharma. Biochem. and Behavior.102, 44.
Takemori AE et al. 1988. J. Pharmacol. Exp. Ther.246, 255.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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