推荐产品
方案
≥99% (HPLC)
质量水平
表单
solid
效能
3.3 nM Ki
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
溶解性
DMSO: 100 mM
ethanol: 50 mM
储存温度
2-8°C
SMILES字符串
[Cl-].Clc1c(ccc(c1)[C@@H]2CC[C@@H](c3c2cccc3)[N+H2]C)Cl
InChI
1S/C17H17Cl2N.ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11;/h2-6,8,10,12,17,20H,7,9H2,1H3;1H/t12-,17-;/m0./s1
InChI key
BLFQGGGGFNSJKA-XHXSRVRCSA-N
一般描述
A very potent uptake inhibitor highly selective for serotonin (Ki = 3.3 nM). Clinically prescribed as an antidepressant drug. Often used in studying major depressive disorders.
生化/生理作用
Primary Target
5-HT uptake transporter
5-HT uptake transporter
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Brunoni, R., et al. 2013. JAMA Psychiatry.70, 383.
Kobayashi, K., et al. 1995. Br. J. Clin. Pharmacol.40, 481.
Heym, J., et al. 1988. J. Clin. Psychiatry.49 Suppl, 40.
Koe, K., et al. 1983. J. Pharmacol. Exp. Ther.226, 700.
Kobayashi, K., et al. 1995. Br. J. Clin. Pharmacol.40, 481.
Heym, J., et al. 1988. J. Clin. Psychiatry.49 Suppl, 40.
Koe, K., et al. 1983. J. Pharmacol. Exp. Ther.226, 700.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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