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Merck
CN
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文件

安全信息

5.05723

Sigma-Aldrich

SCH 23390 Hydrochloride

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别名:
SCH 23390 Hydrochloride, Dopamine Receptor D1/D5 Antagonist, SCH 23390, (R)-(+)-7-Chloro-8-hydroxy-3-methyl­-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride, SCH23390, SCH-23390
经验公式(希尔记法):
C17H18ClNO · xHCl
分子量:
287.78 (free base basis)
MDL编号:
UNSPSC代码:
12352200

检测方案

≥99% (HPLC)

质量水平

形式

solid

效能

0.2 nM Ki

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

off-white

溶解性

water: 100 mM

储存温度

−20°C

InChI

1S/C17H18ClNO.ClH/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12;/h2-6,9-10,15,20H,7-8,11H2,1H3;1H/t15-;/m1./s1

InChI key

OYCAEWMSOPMASE-XFULWGLBSA-N

一般描述

A highly potent and selective dopamine D1-like receptor antagonist with a Ki of 0.2 and 0.3 nM for the D1 and D5 dopamine receptor subtypes, respectively. Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3 nM and 9.3 nM respectively).

生化/生理作用

Primary Target
D1 and D5

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Splinter, M. Y. 2007. Ann. Pharmacother.41, 285.
Pfeiffer, R. F. 2002. Drugs Aging.19, 561.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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