所有图片(1)
别名:
PNU 282987, PNU-282987, N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride, α7 nAChR Agonist, PNU 282987, alpha 7 Nicotinic Acetylcholine Receptor Agonist, PNU 282987, PNU282987
经验公式（希尔记法）:
C14H17ClN2O · xHCl
推荐产品
检测方案
≥99% (HPLC)
质量水平
形式
solid
效能
26 nM Ki
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
off-white
溶解性
water: 100 mM
储存温度
2-8°C
InChI
1S/C14H17ClN2O.ClH/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17;/h1-4,10,13H,5-9H2,(H,16,18);1H/t13-;/m0./s1
InChI key
HSEQUIRZHDYOIX-ZOWNYOTGSA-N
一般描述
A potent agonist highly selective for α7 nAChRs (Ki = 26 nM). Used in investigating the roles of α7 nAChRs in sensory gating, learning and memory, cognitive functions, and treatment of Schizophrenia.
生化/生理作用
Primary Target
α7 nAChRs
α7 nAChRs
Reversible: yes
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Hajós, M., et al., 2010, Curr. Pharm. Des.16, 538.
Bodnar, L., et al., 2005. J. Med. Chem.48, 905.
Hajós, M., et al., 2005. J. Pharmacol. Exp. Ther.312, 1213.
Bodnar, L., et al., 2005. J. Med. Chem.48, 905.
Hajós, M., et al., 2005. J. Pharmacol. Exp. Ther.312, 1213.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
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