推荐产品
方案
≥98% (HPLC)
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
red
溶解性
DMSO: 25 mM
储存温度
−20°C
SMILES字符串
Nc1[c](cc2[o]c3c(nc2c1C(=O)O)c(ccc3)C(=O)O)=O
InChI
1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)
InChI key
FSBKJYLVDRVPTK-UHFFFAOYSA-N
一般描述
A partial, low-potency agonist highly selective for mGlu4 receptors (EC50 >100 µM, no effect on other mGlu subtype receptors). Used in assessing the functional roles of mGlu4 receptors in a variety of research areas, such as excitotoxic cell death, apoptosis, neuroinflammation, inflammation, and neuroimmune communication.
生化/生理作用
Primary Target
mGlu₄ receptors
mGlu₄ receptors
警告
Toxicity: Standard Handling (A)
制备说明
Slight warming is required for complete solubilization.
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Fazio, Francesco, et al. 2012. Mol. Pharmacol.81, 643.
Volpi, C., et al. 2012. Neuropharmacol.63, 501.
Hiramatsu, R., et al. 2008. J. Cell Biochem.103, 42.
Volpi, C., et al. 2012. Neuropharmacol.63, 501.
Hiramatsu, R., et al. 2008. J. Cell Biochem.103, 42.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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