推荐产品
方案
≥98% (HPLC)
质量水平
表单
powder
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
储存温度
10-30°C
InChI
1S/C25H37NO4.C11H8O3/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21;12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2;1-6,12H,(H,13,14)
InChI key
XTZNCVSCVHTPAI-UHFFFAOYSA-N
一般描述
A potent and selective β2-adrenoceptor agonist (EC50 = 5.3 nM) that displays bronchodilator actions. Unlike other β2- adrenoceptor agonists, Salmeterol binds to exo-site domain of β2-AR receptors, producing a slow onset of action and prolonged activation. Clinically used for the treatment of asthma and chronic obstructive pulmonary disease(COPD).
A potent and selective ?2-adrenoceptor agonist (EC50 = 5.3 nM) that displays bronchodilator actions. Unlike other ?2- adrenoceptor agonists, Salmeterol binds to exo-site domain of ?2-AR receptors, producing a slow onset of action and prolonged activation. Clinically used for the treatment of asthma and chronic obstructive pulmonary disease(COPD).
生化/生理作用
Primary Target
→₂-adrenoceptor
→₂-adrenoceptor
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Roberts, J., et al. 1999. Eur. Respir. J.14, 275.
Rennard, S., et al. 2001. Am. J. Respir. Crit. Care Med.163, 1087.
Akabane, H., et al. 2006. Allergol. Int.55, 387.
Rennard, S., et al. 2001. Am. J. Respir. Crit. Care Med.163, 1087.
Akabane, H., et al. 2006. Allergol. Int.55, 387.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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