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检测方案
≥98% (TLC)
质量水平
形式
powder
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
溶解性
water: 50 mg/mL
储存温度
10-30°C
InChI
1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H
InChI key
MYUBYOVCLMEAOH-UHFFFAOYSA-N
一般描述
A non-selective antagonist for α2-adrenoceptors (pKi = 8.01, 7.43, and 7.7 for α2A, α2B, and α2C receptors respectively) and imidazoline receptors. (pKi = 5.90, 7.22 for I1 and I2, receptors respectively). Widely used in studying functions of the nervous systems, such as learning and memory, decision making, reward, attention, addiction, depression, and schizophrenia related to the adrenergic receptors, and blood pressure regulation, pain modulation, and neuroprotection related to the imidazoline receptors.
A non-selective antagonist for ?2-adrenoceptors (pKi = 8.01, 7.43, and 7.7 for ?2A, ?2B, and ?2C receptors respectively) and imidazoline receptors. (pKi = 5.90, 7.22 for I1 and I2, receptors respectively). Widely used in studying functions of the nervous systems, such as learning and memory, decision making, reward, attention, addiction, depression, and schizophrenia related to the adrenergic receptors, and blood pressure regulation, pain modulation, and neuroprotection related to the imidazoline receptors.
生化/生理作用
Primary Target
→₂-adrenoceptor
→₂-adrenoceptor
警告
Toxicity: Toxic (F)
重悬
Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
其他说明
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Humpston, S., et al. 2013. J. of Psychopharmacology, 27, 213.
Dabir, l., 1986. J.Pharmacol.17, 113.
Michel, M., et al. 1992. TIPS13, 369.
Eglen, R., et al. 1998. TiPS19, 381.
Doxey, J., et al. 1984. Br J Pharmacol. 1984. 83, 713.
Gadie, B., 1984. Br J Pharmacol.83, 707.
Dabir, l., 1986. J.Pharmacol.17, 113.
Michel, M., et al. 1992. TIPS13, 369.
Eglen, R., et al. 1998. TiPS19, 381.
Doxey, J., et al. 1984. Br J Pharmacol. 1984. 83, 713.
Gadie, B., 1984. Br J Pharmacol.83, 707.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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