推荐产品
方案
≥99% (HPLC)
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
avoid repeated freeze/thaw cycles
protect from light
颜色
white
溶解性
water: 20 mg/mL
储存温度
2-8°C
SMILES字符串
[S](=O)(=O)(O)C.N1C[C@@H](OCC1)[C@H](Oc3c(cccc3)OCC)c2ccccc2
InChI
1S/C19H23NO3.CH4O3S/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4)/t18-,19-;/m1./s1
InChI key
CGTZMJIMMUNLQD-STYNFMPRSA-N
一般描述
A potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and >10000 nM for rat NET, SERT and DAT, respectively). Displays >1000-fold selectivity over α-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant.
生化/生理作用
Primary Target
Noradrenalin transporter
Noradrenalin transporter
Target Ki: 1.1, 129 and >10000 nM for rat NET, SERT and DAT respectively
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze 9-20°C. Stock solutions are stable for up to 3 months at -20°C.
其他说明
Sacchetti, G., et al. 1999. Br. J. Pharmacol.128, 1332.
Wong, E., et al. 2000. Biol. Psychiatry.47, 818.
Millan, M., et al. 2001. J. Pharmacol. Exp. Ther.298,565.
Owen, J., et al. 2003 Neurosci. Lett.348, 171.
Wong, E., et al. 2000. Biol. Psychiatry.47, 818.
Millan, M., et al. 2001. J. Pharmacol. Exp. Ther.298,565.
Owen, J., et al. 2003 Neurosci. Lett.348, 171.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Repr. 1B
储存分类代码
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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