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Merck
CN

5.00299

SAFC

烟酰胺

EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP, FCC

制药生产

别名:

Nicotinamide, Nicotinamide, Niacinamide, 3-Pyridinecarboxamide

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About This Item

经验公式(希尔记法):
C6H6N2O
CAS号:
分子量:
122.12
MDL编号:
UNSPSC代码:
12352111
EC索引号:
202-713-4

Agency

BP
JP
Ph. Eur.
USP

质量水平

管理合规性

FCC

描述

EMPROVE® ESSENTIAL Ph Eur,BP,USP,JP,FCC

产品线

EMPROVE® ESSENTIAL

表单

solid

自燃温度

480 °C

效能

3530-3540 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rabbit)

技术

API processing | cocrystal formation: suitable

pH值(酸碱度)

6.0-7.5 (20 °C, 50 g/L in H2O)

沸点

150-160 °C/0.0007 hPa

mp

128-131 °C (sublimed)

转变温度

flash point 182 °C

密度

1.40 g/cm3 at 20 °C

应用

liquid formulation
pharmaceutical
solid formulation

储存温度

15-25°C

SMILES字符串

NC(=O)c1cnccc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

InChI key

DFPAKSUCGFBDDF-UHFFFAOYSA-N

一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Nicotinamide is a commonly used ingredient in food and pharmaceutical applications. In pharmaceutical formulations, nicotinamide has been used for a range of different dosage forms.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

302.0 °F - closed cup

闪点(°C)

150 °C - closed cup


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