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经验公式(希尔记法):
C6H6N2O
化学文摘社编号:
分子量:
122.12
UNSPSC Code:
12352111
EC Index Number:
202-713-4
MDL number:
产品名称
烟酰胺, EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP, FCC
SMILES string
NC(=O)c1cnccc1
InChI
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key
DFPAKSUCGFBDDF-UHFFFAOYSA-N
agency
BP
JP
Ph. Eur.
USP
reg. compliance
FCC
description
EMPROVE® ESSENTIAL Ph Eur,BP,USP,JP,FCC
product line
EMPROVE® ESSENTIAL
form
solid
autoignition temp.
480 °C
potency
3530-3540 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rabbit)
technique(s)
API processing | cocrystal formation: suitable
pH
6.0-7.5 (20 °C, 50 g/L in H2O)
bp
150-160 °C/0.0007 hPa
mp
128-131 °C (sublimed)
transition temp
flash point 182 °C
density
1.40 g/cm3 at 20 °C
application(s)
liquid formulation
pharmaceutical
solid formulation
storage temp.
15-25°C
Quality Level
Application
Nicotinamide is a commonly used ingredient in food and pharmaceutical applications. In pharmaceutical formulations, nicotinamide has been used for a range of different dosage forms.
General description
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
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