489350
L-(–)-Norepinephrine-(+)-bitartrate
α,β-Adrenergic agonist.
别名:
L-(−)-Norepinephrine-(+)-bitartrate salt monohydrate, R(–)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol-(+)-tartrate, Noradrenaline
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所有图片(2)
About This Item
经验公式（希尔记法）:
C8H11NO3 · C4H6O6 · H2O
CAS号:
分子量:
337.28
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77
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质量水平
方案
≥97% (LC/MS)
表单
crystalline solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated
颜色
white
溶解性
water: 1 mg/mL
运输
ambient
储存温度
2-8°C
SMILES字符串
NC[C@H](O)c1cc(c(cc1)O)O.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O
InChI
1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1
InChI key
LNBCGLZYLJMGKP-LUDZCAPTSA-N
一般描述
α,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors.
α,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors. Oxidation sensitive.
生化/生理作用
Cell permeable: no
Primary Target
α,β-Adrenergic agonist
α,β-Adrenergic agonist
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)
制备说明
Addition of sodium bisulfite (at a final concentration of 0.1%) is necessary to prevent oxidation.
重悬
Following reconstituiton, refrigerate (4°C). Stock solutions are stable for up to 5 days at 4°C.
其他说明
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Yang, H., et al. 1996. Hypertension 27, 1277.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险声明
危险分类
Acute Tox. 1 Dermal - Acute Tox. 2 Oral
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
H Yang et al.
Hypertension (Dallas, Tex. : 1979), 27(6), 1277-1283 (1996-06-01)
Norepinephrine causes downregulation of angiotensin II (Ang II) receptors in Wistar-Kyoto rat (WKY) brain neuronal cultures. The aim of this study was to compare the cross talk between Ang II and alpha1-adrenergic receptors in these neuronal cultures. Norepinephrine causes a
Inbal Rachmin et al.
Experimental dermatology, 30(4), 578-587 (2021-02-19)
Hair greying depends on the altered presence and functionality of hair follicle melanocytes. Melanocyte stem cells (MelSCs) reside in the bulge of hair follicles and give rise to migrating and differentiating progeny during the anagen phase. Ageing, genotoxic stress, redox
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