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Merck
CN
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文件

487952

Sigma-Aldrich

NOC-7

A nitric oxide (NO) donor similar to NOC-5 but with a much shorter half-life of NO release.

别名:

NOC-7, 3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine

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About This Item

经验公式(希尔记法):
C5H14N4O2
分子量:
162.19
UNSPSC代码:
12352200

质量水平

检测方案

≥90% (HPLC)

形式

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)
protect from light

颜色

white

溶解性

0.1 M NaOH: soluble
water: soluble

运输

ambient

储存温度

−20°C

InChI

1S/C5H14N4O2/c1-6-4-3-5-8(2)9(11)7-10/h6,11H,3-5H2,1-2H3

InChI key

AXAGAUVQMYPYHM-UHFFFAOYSA-N

一般描述

A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) but with a much shorter half-life of NO release. Half-life (t½) in PBS, pH 7.4 is 10 minutes at 22°C. Useful as a short-acting nitrovasodilator. Relatively stable in alkaline solution (pH ≥10.0).
A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) but with a much shorter half-life of NO release. Useful as a short-acting nitrovasodilator. Half-life (t½) of NO release = 10 min (PBS, pH 7.4, 22°C).

生化/生理作用

Cell permeable: no
Primary Target
A nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Irritant (B)

重悬

Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O jut prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.

其他说明

Zhang, P., et al. 1996. Circulation94, 2235.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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