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Merck
CN

481990

尼日利亚菌素钠盐，吸水链霉菌

Disrupts the membrane potential and stimulates ATPase activity in mitochondria.

别名:

尼日利亚菌素钠盐，吸水链霉菌, 抗生素K178

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关于此项目

经验公式（希尔记法）:
C40H67O11 · Na
化学文摘社编号:
28643-80-3
分子量:
746.94
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
MFCD00036825

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产品名称

尼日利亚菌素钠盐，吸水链霉菌, Disrupts the membrane potential and stimulates ATPase activity in mitochondria.

InChI

1S/C40H68O11.Na/c1-21-11-12-28(46-33(21)26(6)36(42)43)17-29-18-30(45-10)27(7)40(48-29)25(5)19-38(9,51-40)32-13-14-37(8,49-32)35-23(3)16-31(47-35)34-22(2)15-24(4)39(44,20-41)50-34;/h21-35,41,44H,11-20H2,1-10H3,(H,42,43);/q;+1/p-1/t21-,22-,23-,24+,25?,26?,27+,28+,29+,30+,31+,32?,33?,34-,35?,37?,38?,39-,40+;/m0./s1

InChI key

MOYOTUKECQMGHE-KKCUGXASSA-M

assay

≥98% (TLC)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

chloroform: soluble
ethanol: soluble
ethyl acetate: soluble

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Other Notes

由于该运输中有害物质的性质，您的订单可能需要支付额外的运输费用。某些尺寸的产品可免除其他有害材料的运输费用。请与您当地的销售办事处联系，以获取有关这些费用的更多信息。
Moriyama, Y., et al. 1994.J. Biochem.115, 213.
Eytan, G.D., et al. 1990.J. Biol. Chem.265, 12949.
Alonso, M.A., and Carrasco, L. 1981.FEBS Lett.127, 112.

Preparation Note

在重悬后分装并冻存。储备液可在-20°C稳定1个月。

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biochem/physiol Actions

产物不与ATP竞争。
可逆：否
细胞渗透性：否
首要靶标
破坏膜电位并刺激线粒体中的ATP酶活性。

Disclaimer

毒性：有毒（F）

General description

一种可催化碱金属电子中性交换H+（反向运输）的单羧酸。按以下特异性排列进行单价阳离子跨膜运输：K+>Rb+>Cs+>>Na+。一种可通过促进离子跨膜扩散而杀死细菌的抗生素。破坏膜电位并刺激线粒体ATP酶活性。
破坏膜电位并刺激线粒体中的ATP酶活性。按以下特异性排列进行单价阳离子跨膜运输：K+>Rb+>Cs+>>Na+。

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H319

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

法规信息

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