480747
Neurogenesis Inducer V, KHS101
A blood brain barrier permeable pyrimidinyl-aminothiazole compound that specifically interacts with TACC3 (transforming acidic coiledcoil-containing protein 3) and promotes nuclear localization of ARNT2 (aryl-hydrocarbon receptor nuclear translocator 2).
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所有图片(2)
别名:
Neurogenesis Inducer V, KHS101, N⁴-Isobutyl-N²-((2-phenylthiazol-4-yl)methyl)pyrimidine-2,4-diamine
经验公式（希尔记法）:
C18H21N5S
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质量水平
检测方案
≥95% (HPLC)
形式
resin (Sticky)
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
yellow
溶解性
DMSO: 100 mg/mL
运输
wet ice
储存温度
2-8°C
一般描述
A blood brain barrier permeable pyrimidinyl-aminothiazole compound that specifically interacts with TACC3 (transforming acidic coiledcoil-containing protein 3) and promotes nuclear localization of ARNT2 (aryl-hydrocarbon receptor nuclear translocator 2). Shown to significantly induce neuronal differentiation of cultured rat hippocampal NPCs (neural progenitor cells; EC50 ~ 1 µM) and in adult rats (6 mg/kg, s.c.) and suppress proliferation.
包装
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
其他说明
Wurdak, H., et al. 2010. Proc. Natl. Acad. Sci. USA107, 16542
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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