480746-M
Neuronal Differentiation Inducer IV
A cell-permeable quinoxaline compound that is shown to induce neuronal differentiation in PC12 and rat MSC (mesenchymal stem cell) cultures with high efficiency.
别名:
Neuronal Differentiation Inducer IV, N-Hydroxy-2-oxo-3-(3-phenylpropyl)-1,2-dihydroquinoxaline-6-carboxamide, 2-Oxo-3-(3-phenyl-propyl)-1,2-dihydro-quinoxaline-6-carboxylic acid hydroxyamide
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所有图片(1)
About This Item
经验公式（希尔记法）:
C18H17N3O3
分子量:
323.35
UNSPSC代码:
12352200
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方案
≥95% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
off-white
溶解性
DMSO: 25 mg/mL, pale yellow
储存温度
2-8°C
一般描述
A cell-permeable quinoxaline compound that is shown to induce neuronal differentiation in PC12 and rat MSC (mesenchymal stem cell) cultures with high efficiency (>95%; 20 µM for 48 h) as determined by Nissl staining, expressions of neuronal markers and genes (β-III tubulin, NSE, Chrna2, Chrnb2, Chrm4, Foxo2, Sizn 1), as well as by whole-cell electrophysiology measurements, without any concomitant astroglial differentiation induction as indicated by the absence of GFAP (glial fibrillary acidic protein) expression.
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Kim, N.R., et al. 2009. J. Med. Chem.52, 7931.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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