产品名称
Anti-Myeloperoxidase Rabbit pAb, liquid, Calbiochem®
biological source
rabbit
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
dilution
(ELISA (1:4000)
Immunoelectrophoresis )
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MPO(4353)
Application
ELISA (≥ 1:4000)
Immunoelectrophoresis (see comments)
Immunoelectrophoresis (see comments)
Disclaimer
Toxicity: Standard Handling (A)
General description
Rabbit polyclonal antibody purified by ammonium sulfate precipitation followed by DEAE-Sephacel ion exchange chromatography. Recognizes the myeloperoxidase protein.
Recognizes myeloperoxidase in human neutrophil granules.
This Anti-Myeloperoxidase Rabbit pAb is validated for use in ELISA, Immunoelectrophoresis for the detection of Myeloperoxidase.
Immunogen
Human
purified, human neutrophil myeloperoxidase
Other Notes
Generates a single arc by immunoelectrophoresis against human neutrophil granule extract and purified MPO. Variables associated with assay conditions will dictate the proper working dilution.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In PBS.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Sean E Gill et al.
American journal of respiratory cell and molecular biology, 55(2), 243-251 (2016-03-05)
Although neutrophils play critical roles in innate immunity, in excess these cells cause severe tissue damage. Thus, neutrophil activation must be tightly regulated to prevent indiscriminant damage. Previously, we reported that mice lacking matrix metalloproteinase (MMP) 7 are protected from
Martina Maritati et al.
Frontiers in microbiology, 15, 1417049-1417049 (2024-06-24)
The accurate distinction between periprosthetic joint infections (PJI) and aseptic failures (AF) is of paramount importance due to differences in treatment. However, this could be challenging by using the current criteria. Various synovial fluid biomarkers are being assessed to improve
Tobias Deuse et al.
Nature, 509(7502), 641-644 (2014-04-22)
Despite the introduction of antiproliferative drug-eluting stents, coronary heart disease remains the leading cause of death in the United States. In-stent restenosis and bypass graft failure are characterized by excessive smooth muscle cell (SMC) proliferation and concomitant myointima formation with
Volker Rudolph et al.
Nature medicine, 16(4), 470-474 (2010-03-23)
Observational clinical and ex vivo studies have established a strong association between atrial fibrillation and inflammation. However, whether inflammation is the cause or the consequence of atrial fibrillation and which specific inflammatory mediators may increase the atria's susceptibility to fibrillation
Kashish Manchanda et al.
Arteriosclerosis, thrombosis, and vascular biology, 38(8), 1859-1867 (2018-06-16)
Objective- The leukocyte heme-enzyme MPO (myeloperoxidase) exerts proinflammatory effects on the vascular system primarily linked to its catalytic properties. Recent studies have shown that MPO, depending on its cationic charge, mediates neutrophil recruitment and activation. Here, we further investigated MPO's
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