跳转至内容
Merck
CN
所有图片(1)

主要文件

475882-M

Millipore

ML-9, Hydrochloride

A cell-permeable, reverisible and ATP-competitive inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM).

别名:

ML-9, Hydrochloride, 1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C15H17ClN2O2S · xHCl
分子量:
324.83 (free base basis)
MDL编号:
UNSPSC代码:
12352200

质量水平

方案

≥98% (TLC)

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)
protect from light

颜色

white

溶解性

50% ethanol: 10 mg/mL

储存温度

2-8°C

SMILES字符串

[S](=O)(=O)(N3CCNCCC3)c1c2c(c(ccc2)Cl)ccc1.[Cl-].[H+]

InChI

1S/C15H17ClN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H

InChI key

ZNRYCIVTNLZOGI-UHFFFAOYSA-N

一般描述

A cell-permeable, reverisible and ATP-competitive inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM). Also inhibits catecholamine secretion in intact and permeabilized chromaffin cells.

生化/生理作用

Primary Target
Mlck
Target Ki: 3.8 µM, 32 µM, 54 µM against myosin light chain kinase, protein kinase A, and protein kinase C, respectively

警告

Toxicity: Standard Handling (A)

制备说明

Further dilute with aqueous buffer just prior to use.

重悬

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.

其他说明

Reig, J.A., et al. 1993. Neurochem. Res. 18, 317.
Nagatsu, T., et al. 1987. Biochem. Biophys. Res. Commun.143, 1045.
Saitoh, M., et al. 1987. J. Biol. Chem.262, 7796.
Saitoh, M., et al. 1986. Biochem. Biophys. Res. Commun.140, 280.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门