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安全信息

475820

Millipore

丝裂霉素C，头状链霉菌，无载体

Antibiotic and carcinostatic agent. Inhibits DNA synthesis by cross-linking DNA at guanine and adenine residues; disrupts base pairing. Induces apoptosis in gastric cancer cells.

别名:

丝裂霉素C，头状链霉菌，无载体

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About This Item

经验公式（希尔记法）:
C15H18N4O5
CAS号:
50-07-7
分子量:
334.33
MDL编号:
MFCD00078109
UNSPSC代码:
12352200

质量水平

100

方案

≥95% (HPLC)

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

purple

溶解性

water: <1 mg/mL
methanol: 5 mg/mL

运输

ambient

储存温度

2-8°C

InChI

1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1

InChI key

NWIBSHFKIJFRCO-WUDYKRTCSA-N

一般描述

抗生素和抗癌剂。通过在鸟嘌呤和腺嘌呤残基处交联DNA抑制DNA合成；破坏碱基对。诱导胃癌细胞凋亡。将细胞周期阻滞在G2期。
抗生素和抗癌剂。通过在鸟嘌呤和腺嘌呤残基处交联DNA抑制DNA合成；破坏碱基对。诱导胃癌细胞凋亡。将细胞周期阻滞在G2期。功效：≥970 µg/mg。

生化/生理作用

功效： ≥ 970 μg/mg丝裂霉素C

警告

毒性：高毒性 & 致癌性/致畸性（I）

重悬

复溶后，等分并冷冻保存（-20°C）。贮备液在-20°C下可稳定保存至多3个月。

其他说明

Kryt, F.A., et al. 1996.Blood 89, 938.
Schwartz, G.K., et al. 1995.J. Natl.Cancer Inst.87, 1394.
Folnan, R.S., 1993.Oncology 50, 24.
Tomasz, M., et al. 1987.Science 235, 1204.
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法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险声明

H300,H351

危险分类

Acute Tox. 2 Oral - Carc. 2

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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