推荐产品
质量水平
检测方案
≥98% (TLC)
形式
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
溶解性
water: 1 mg/mL
DMSO: 20 mg/mL
ethanol: 20 mg/mL
运输
ambient
储存温度
−20°C
InChI
1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1
InChI key
ZBOMSHVRJSJGNR-JBNKPAQWSA-N
一般描述
冈田酸的水溶性类似物（目录号495604）。抑制蛋白磷酸酶1和2A。
生化/生理作用
主要靶标
PP1，PP2A
PP1，PP2A
产物不与ATP竞争。
可逆：否
细胞渗透性：否
警告
毒性：有毒（F）
其他说明
Gjertsen, B.T., et al. 1994.J. Cell Sci.107, 3363.
Kiguchi, K., et al. 1994.Cell Growth Differentiation5, 995.
Ohaka, Y., et al. 1993.Biochem.Biophys.Res. Commun.197, 916.
Gopalakrishna, R., et al. 1992.Biochem.Biophys.Res. Commun.189, 950.
Kreienbuhl, P., et al. 1992.Blood80, 2911.
Normura, M., et al. 1992.Biochemistry31, 11915.
Song, Q., et al. 1992.J. Cell Physiol.153, 550.
Tada, T., et al. 1992.Immunopharmacol.24, 17.
Cohen, P., et al. 1990.Trends Biochem.Sci.15, 98.
Cohen, P., et al. 1989.Annu.Rev. Biochem.58, 453.
Cohen, P., and Cohen, P.T.W.1989.J. Biol. Chem.264, 21435.
Haystead, T.A.J., et al. 1989.Nature337, 78.
Kiguchi, K., et al. 1994.Cell Growth Differentiation5, 995.
Ohaka, Y., et al. 1993.Biochem.Biophys.Res. Commun.197, 916.
Gopalakrishna, R., et al. 1992.Biochem.Biophys.Res. Commun.189, 950.
Kreienbuhl, P., et al. 1992.Blood80, 2911.
Normura, M., et al. 1992.Biochemistry31, 11915.
Song, Q., et al. 1992.J. Cell Physiol.153, 550.
Tada, T., et al. 1992.Immunopharmacol.24, 17.
Cohen, P., et al. 1990.Trends Biochem.Sci.15, 98.
Cohen, P., et al. 1989.Annu.Rev. Biochem.58, 453.
Cohen, P., and Cohen, P.T.W.1989.J. Biol. Chem.264, 21435.
Haystead, T.A.J., et al. 1989.Nature337, 78.
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法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
WGK
WGK 3
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