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Merck
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454582

Sigma-Aldrich

Anti-NMDAR 2B (984-1104) Rabbit pAb

lyophilized, Calbiochem®

别名:

Anti-N-Methyl-D-Aspartate Receptor 2B-Subunit

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.43

生物来源

rabbit

质量水平

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized

不包含

preservative

种属反应性

rat, fish, mouse, human

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

同位素/亚型

IgG

运输

ambient

储存温度

−20°C

靶向翻译后修饰

unmodified

一般描述

Immunoaffinty purified rabbit polyclonal antibody. Recognizes the ~180 kDa NMDAR2B subunit of the NMDA receptor.
Recognizes the ~180 kDa NMDA receptor NR2B subunit.
This Anti-NMDAR 2B (984-1104) Rabbit pAb is validated for use in Immunoblotting, Immunohistochemistry, Immunoprecipitation for the detection of NMDAR 2B (984-1104).

免疫原

Rat Brain
a recombinant fusion protein consisting of amino acids 984-1104 of rat brain NMDAR 2B-subunit

应用

Immunoblotting (1:1000)

Immunohistochemistry (1:1000-1:2000)

Immunoprecipitation (see comments)

警告

Toxicity: Standard Handling (A)

外形

Lyophilized from 5 mM ammonium bicarbonate.

重悬

Reconstitute in 50 µl PBS. Following reconstitution, aliquot and freeze (-20°C). Avoid freeze thaw cycles of reconstituted solution.

其他说明

Does not cross-react with NMDAR2A or NMDAR2C. Please refer to the certificate of analysis for lot-specific immunoprecipitation volume. Variables associated with assay conditions will dictate the proper working dilution.
Wang, Y.H., et al. 1995. J. Neurochem.65, 176.
Petralia, R.S., et al. 1994. J. Neurosci.14, 6102.
Ishii, T., et al. 1993. J. Biol. Chem.268, 2836.
Monyer, H., et al. 1992. Nature256, 1217.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Ainhoa Plaza-Zabala et al.
Neuroscience letters, 557 Pt B, 101-106 (2013-11-23)
Hypocretin peptides are critical for the effects of cocaine on excitatory synaptic strength in the ventral tegmental area (VTA). However, little is known about their role in cocaine-induced synaptic plasticity in the nucleus accumbens (NAc). First, we tested whether hypocretin-1
Carrie R Ferrario et al.
PloS one, 7(8), e40898-e40898 (2012-08-08)
We previously showed that the time-dependent intensification ("incubation") of cue-induced cocaine seeking after withdrawal from extended-access cocaine self-administration is accompanied by accumulation of Ca(2+)-permeable AMPA receptors (CP-AMPARs) in the rat nucleus accumbens (NAc). These results suggest an enduring change in
Leonardo Santana Novaes et al.
Translational psychiatry, 11(1), 18-18 (2021-01-09)
The persistence of anxiety and the deficit of fear memory extinction are both phenomena related to the symptoms of a trauma-related disorder, such as post-traumatic stress disorder (PTSD). Recently we have shown that single acute restraint stress (2 h) in rats
Daniela Bonini et al.
Neural plasticity, 2016, 7267865-7267865 (2016-03-12)
Clinical studies on patients with stress-related neuropsychiatric disorders reported functional and morphological changes in brain areas where glutamatergic transmission is predominant, including frontal and prefrontal areas. In line with this evidence, several preclinical works suggest that glutamate receptors are targets
Carrie R Ferrario et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 35(3), 818-833 (2009-11-20)
alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionate receptor (AMPAR) surface expression in the nucleus accumbens (NAc) is enhanced after withdrawal from repeated cocaine exposure. However, it is unclear whether this contributes to the expression of locomotor sensitization and whether similar changes can be observed in other

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