444300
褪黑素标准液
A hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals.
别名:
褪黑素
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关于此项目
经验公式（希尔记法）:
C13H16N2O2
化学文摘社编号:
分子量:
232.28
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
Storage condition:
OK to freeze
protect from light
protect from light
产品名称
褪黑素标准液, A hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals.
SMILES string
[nH]1c2c(c(c1)CCNC(=O)C)cc(cc2)OC
InChI
1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
InChI key
DRLFMBDRBRZALE-UHFFFAOYSA-N
description
Merck USA index - 14, 5816
assay
≥98% (HPLC)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
white to slightly yellow
solubility
methanol: 50 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
主要靶标
大鼠NOS
大鼠NOS
产物不与ATP竞争。
可逆：否
细胞渗透性：否
Disclaimer
毒性：标准处理（A）
General description
一种被假定为光周期哺乳动物中光诱导的抗促性腺激素活性的介质的激素。抵消依托泊苷在骨髓细胞中的凋亡作用。褪黑激素受体与G蛋白系统偶联。具有抗氧化剂性能。对Aβ肽具有神经保护作用。抑制大鼠小脑一氧化氮合酶（NOS）。还充当过氧亚硝酸盐清除剂。
一种被假定为光周期哺乳动物中光诱导的抗促性腺激素活性的介质的激素。抵消依托泊苷在骨髓细胞中的凋亡作用。褪黑激素受体与G蛋白系统偶联。抑制大鼠小脑一氧化氮合酶（NOS）。
Other Notes
Pappolla, M.A., et al. 2002.J. Pineal Res.32, 135.
Reiter, R.J., and Tan, D.X.2002.Ann.N.Y.Acad.Sci.957, 341.
Cuzzocrea, S., et al. 1998.J. Pineal Res. 25, 24.
Maestroni, G.J., et al. 1994.Cancer Res. 54, 2429.
Pozo, D., et al. 1994.Life Sciences55, PL455.
Reiter, R.J., and Tan, D.X.2002.Ann.N.Y.Acad.Sci.957, 341.
Cuzzocrea, S., et al. 1998.J. Pineal Res. 25, 24.
Maestroni, G.J., et al. 1994.Cancer Res. 54, 2429.
Pozo, D., et al. 1994.Life Sciences55, PL455.
Preparation Note
复溶后，等分并冷冻保存（-20°C）。贮备液在-20°C下可稳定保存至多3个月。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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