444244
MMP-2 Inhibitor I
The MMP-2 Inhibitor I, also referenced under CAS 10335-69-0, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
别名:
MMP-2 Inhibitor I, cis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
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About This Item
推荐产品
质量水平
方案
≥98% (HPLC)
表单
solid
效能
1.7 mM Ki
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
溶解性
DMSO: 2 mg/mL
ethanol: 3 mg/mL
运输
wet ice
储存温度
−20°C
SMILES字符串
N(O)C(=O)CCCCCCC\C=C/CCCCCCCC
InChI
1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(20)19-21/h9-10,21H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
InChI key
LTXHELLMCCEDJG-KTKRTIGZSA-N
一般描述
A cell-permeable, potent inhibitor of MMP-2 that acts in a dose-dependent manner (Ki = 1.7 µM).
Potent inhibitor of MMP-2 (gelatinase A). Inhibits MMP-2 in a dose dependent manner (Ki = 1.7 µM)
生化/生理作用
Cell permeable: yes
Primary Target
MMP-2
MMP-2
Product does not compete with ATP.
Reversible: no
包装
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
重悬
Unstable in solution; reconstitute just prior to use.
其他说明
Berton, A., et. al. 2001. J. Biol. Chem.276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci.878, 647.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci.878, 647.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
The FEBS journal, 281(10), 2353-2365 (2014-03-25)
Ste20-related proline/alanine-rich kinase (SPAK) plays a role in regulating many biological activities, and interacts with K-Cl co-transporter 3 (KCC3); however, the importance of SPAK for KCC3 function has not been demonstrated. Here, we investigated the role of SPAK in KCC3-regulated
Cells, 11(9) (2022-05-15)
Astrocytes regulate important functions in the brain, and their dysregulation has been linked to the etiology of neurodegenerative diseases, such as Alzheimer's disease (AD). The role of astroglia in human AD remains enigmatic, owing to the limitations of animal models
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