444218
MMP-3 Inhibitor I
The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
别名:
MMP-3 Inhibitor I, Ac-RCGVPD-NH2, Stromelysin-1 Inhibitor
产品名称
MMP-3 Inhibitor I, The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
assay
≥90% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Cell permeable: no
Primary Target
MMP-3
MMP-3
Product does not compete with ATP.
Reversible: no
Target IC50: 5 µM against MMP-3
Disclaimer
Toxicity: Standard Handling (A)
General description
Inhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain.
Inhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM).
Other Notes
Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂
Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
Physical form
Supplied as a trifluroacetate salt.
Preparation Note
Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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