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Merck
CN
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主要文件

444218

Sigma-Aldrich

MMP-3 Inhibitor I

The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

别名:

MMP-3 Inhibitor I, Ac-RCGVPD-NH₂, Stromelysin-1 Inhibitor

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About This Item

经验公式(希尔记法):
C27H46N10O9S
分子量:
686.78
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

方案

≥90% (HPLC)

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)

颜色

white

溶解性

water: 1 mg/mL

运输

ambient

储存温度

−20°C

一般描述

Inhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain.
Inhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM).

生化/生理作用

Cell permeable: no
Primary Target
MMP-3
Product does not compete with ATP.
Reversible: no
Target IC50: 5 µM against MMP-3

警告

Toxicity: Standard Handling (A)

序列

Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂

外形

Supplied as a trifluroacetate salt.

重悬

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.

其他说明

Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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