437694
Dihydro-DL-α-Lipoic Acid
≥95% (TLC), NO scavenger, liquid
别名:
DL-α-Lipoic Acid, Dihydro-, DHLA, Dihydrolipoic Acid, Thiocytic Acid, Dihydro-
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关于此项目
经验公式（希尔记法）:
C8H16O2S2
化学文摘社编号:
分子量:
208.34
UNSPSC Code:
12352106
NACRES:
NA.77
MDL number:
Assay:
≥95% (TLC)
Form:
liquid
Quality level:
Storage condition:
OK to freeze, protect from light
产品名称
DL-α-Lipoic Acid, Dihydro-, An effective antioxidant.
storage temp.
2-8°C
SMILES string
SC(CCS)CCCCC(=O)O
InChI
1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10)
InChI key
IZFHEQBZOYJLPK-UHFFFAOYSA-N
assay
≥95% (TLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
light yellow
solubility
ethanol: 50 mg/mL
shipped in
ambient
Quality Level
General description
An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α1-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals
Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Other Notes
Packer, L., et al. 1997. Adv. Pharmacol. 38, 79.
Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.
Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
348.1 °F - Cleveland open cup
flash_point_c
175.6 °C - Cleveland open cup
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