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product name
红海海绵素B，Latrunculia magnifica, Latrunculin B, CAS 76343-94-7, is a unique marine toxin that inhibits actin polymerization and disrupts microfilament organization. It is 10 to 100-fold more potent than cytochalasins.
质量水平
检测方案
≥95% (HPLC)
形式
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
off-white to yellow
溶解性
DMSO: 25 mg/mL
ethanol: 25 mg/mL
methanol: 50 mg/mL
运输
ambient
储存温度
−20°C
InChI
1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17+,20-/m1/s1
InChI key
NSHPHXHGRHSMIK-JRIKCGFMSA-N
一般描述
一种结构独特的海洋毒素。在体外抑制肌动蛋白的聚合并破坏微丝组织以及微丝介导的过程。效力比细胞松弛素高 10 至 100 倍。
一种结构独特的海洋毒素。在体外抑制肌动蛋白的聚合并破坏微丝组织以及微丝介导的过程；效力比细胞松弛素高 10 至 100 倍。
生化/生理作用
主靶
肌动蛋白聚合
肌动蛋白聚合
产物不与ATP竞争。
可逆：否
细胞渗透性：否
警告
毒性：有害（C）
其他说明
Spector, I., et al. 1989.Cell Motil.Cytoskeleton13, 127.
de Oliveira, C.A., and Mantovani, B. 1988.Life Sci.43, 1825.
Coue, M., et al. 1987.FEBS Lett.213, 316.
Spector, I., et al. 1983.Science219, 493.
de Oliveira, C.A., and Mantovani, B. 1988.Life Sci.43, 1825.
Coue, M., et al. 1987.FEBS Lett.213, 316.
Spector, I., et al. 1983.Science219, 493.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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