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Merck
CN
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文件

420321

Sigma-Aldrich

KT5823

Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).

别名:

KT5823, PKG Inhibitor VII

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About This Item

经验公式(希尔记法):
C29H25N3O5
分子量:
495.53
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

white

溶解性

DMSO: 1 mg/mL
DMF: soluble

运输

ambient

储存温度

−20°C

InChI

1S/C29H25N3O5/c1-28-29(36-4,27(34)35-3)13-20(37-28)31-18-11-7-5-9-15(18)22-23-17(14-30(2)26(23)33)21-16-10-6-8-12-19(16)32(28)25(21)24(22)31/h5-12,20H,13-14H2,1-4H3/t20-,28+,29+/m1/s1

InChI key

QTYMDECKVKSGSM-YMUMJAELSA-N

一般描述

Highly specific cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM). Inhibits protein kinase C (Ki = 4.0 µM) and protein kinase A (Ki >10.0 µM) at higher concentrations.
Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).

生化/生理作用

Cell permeable: yes
Primary Target
PKG
Product competes with ATP.
Reversible: yes
Target Ki: 234 nM against protein kinase G

警告

Toxicity: Standard Handling (A)

制备说明

Further dilute with aqueous buffers just prior to use.

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Grider, J.R. 1993. Am. J. Physiol.264, G334.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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