跳转至内容
Merck
CN
所有图片(1)

主要文件

420318

Sigma-Aldrich

红藻氨酸

≥98% (HPLC), solid, amino acid receptor agonist, Calbiochem®

别名:

红藻氨酸, 2-羧基-4-(1-甲基乙烯基)-3-吡咯烷乙酸

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C10H15NO4
CAS号:
分子量:
213.23
MDL编号:
UNSPSC代码:
12352106
NACRES:
NA.77

产品名称

红藻氨酸, An excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for ³H-kainate binding in rat striatum).

质量水平

方案

≥98% (HPLC)

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

off-white

溶解性

dilute base: 10 mg/mL
water: 10 mg/mL

运输

ambient

储存温度

2-8°C

SMILES字符串

[N+H2]1[C@@H]([C@H]([C@H](C1)C(=C)C)CC(=O)O)C(=O)[O-]

InChI

1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1

InChI key

VLSMHEGGTFMBBZ-OOZYFLPDSA-N

一般描述

对海藻酸盐受体亚型具有选择性的兴奋性氨基酸受体激动剂(对于大鼠纹状体中3H-海藻酸盐结合,Ki=21 nM)。还激活AMPA受体。

生化/生理作用

21 nM,对于大鼠纹状体中3H-海藻酸盐结合
主要靶标
红藻氨酸受体亚型
产物不与ATP竞争。
可逆:否
细胞渗透性:否

警告

毒性:有害(C)

其他说明

Niu, L., et al. 1996.Biochemistry35, 2030.
Watkins, J.C. and Evans, R.H.1981.Annu.Rev. Pharmacol.Toxicol.21, 165.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Zi-Yang Liu et al.
Cell & bioscience, 14(1), 66-66 (2024-05-24)
Human patients often experience an episode of serious seizure activity, such as status epilepticus (SE), prior to the onset of temporal lobe epilepsy (TLE), suggesting that SE can trigger the development of epilepsy. Yet, the underlying mechanisms are not fully
Jasmin Herz et al.
Neuron, 109(22), 3609-3618 (2021-11-19)
Mechanisms governing how immune cells and their derived molecules impact homeostatic brain function are still poorly understood. Here, we elucidate neuronal mechanisms underlying T cell effects on synaptic function and episodic memory. Depletion of CD4 T cells led to memory deficits and
Joshua D Rieskamp et al.
iScience, 26(7), 107068-107068 (2023-08-03)
Within the adult mammalian dentate gyrus (DG) of the hippocampus, glutamate stimulates neural stem cell (NSC) self-renewing proliferation, providing a link between adult neurogenesis and local circuit activity. Here, we show that glutamate-induced self-renewal of adult DG NSCs requires glutamate

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门