InChI key
PBGKTOXHQIOBKM-FHFVDXKLSA-N
biological source
yeast (Pichia pastoris)
description
Merck USA index - 14, 4980
sterility
non-sterile
assay
≥95—105%
form
solid
specific activity
≥25 IU/mg (dry basis)
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<10 EU/mg Endotoxin (EU/mg protein)
color
white to off-white
solubility
0.01 M HCl: soluble
shipped in
wet ice
storage temp.
−20°C
Quality Level
Disclaimer
毒性:标准处理(A)
General description
在巴斯德毕赤酵母中表达的重组人胰岛素(锌)。由胰腺β-细胞产生的肽合成代谢激素。增加线粒体内蛋白、脂肪、糖原的合成及底物氧化。与膜胰岛素受体相互作用引起其生物学作用。
Other Notes
Mohan, C., et al. 1989.Curr.Topics Cell.Reg.30, 105.
Johnson, I.S.1983.Science219, 632.
Johnson, I.S.1983.Science219, 632.
≥25 IU/mg (dry basis).
Preparation Note
复溶后,储存在冰箱中(4°C)。储备液可在4°C最长稳定6周。
胰岛素在pH值4.5-7.0中几乎不溶。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
nwg
法规信息
高风险级别生物产品-Merck
此项目有
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The aim of the present study was to determine the role of individual PHLPP isoforms in insulin signaling and insulin resistance in neuronal cells. PHLPP isoforms were either silenced or overexpressed individually, and the effects were observed on individual Akt
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Role of CDK5 and its inhibition in various neuronal processes and functions are well established. However, role of CDK5 and its inhibition in neuronal insulin-signaling and-resistance is not yet explored. In the present study, we investigated the effect of CDK5
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Extraction of integral membrane proteins with poly(styrene-co-maleic acid) provides a promising alternative to detergent extraction. A major advantage of extraction using copolymers rather than detergent is the retention of the lipid bilayer around the proteins. Here we report the first
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