385880
Hsp25 Kinase Inhibitor
The Hsp25 Kinase Inhibitor controls the biological activity of Hsp25 KInase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
Hsp25 Kinase Inhibitor, KKKALNRQLGVAA, MK2 Inhibitor, MAPKAP Kinase-2 Inhibitor, MK2 Inhibitor, KKKALNRQLGVAA, MAPKAP Kinase-2 Inhibitor
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所有图片(1)
About This Item
经验公式（希尔记法）:
C61H113N21O16
分子量:
1396.68
UNSPSC代码:
12352200
NACRES:
NA.77
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质量水平
方案
≥98% (HPLC)
表单
lyophilized solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
颜色
white
溶解性
DMSO: soluble
water: soluble
运输
ambient
储存温度
−20°C
一般描述
A 13-residue, cell-permeable peptide that acts as a potent and selective inhibitor of mammalian heat-shock protein (Hsp25) kinase. Inhibits Hsp25 kinase competitively with respect to the substrate peptide (Ki = 8.1 µM) and non-competitive with respect to ATP (Ki = 134 µM). [Hsp 25 kinase is also called mitogen-activated protein kinase-activated protein kinase-2 (MK2).]
生化/生理作用
Cell permeable: yes
Primary Target
(Hsp25) kinase
(Hsp25) kinase
Product does not compete with ATP.
Reversible: no
Target Ki: 8.1 µM against (Hsp25) kinase
警告
Toxicity: Standard Handling (A)
序列
H-Lys-Lys-Lys-Ala-Leu-Asn-Arg-Gln-Leu-Gly-Val-Ala-Ala-OH
外形
Supplied as a trifluoroacetate salt.
重悬
Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to months at -20°C.
其他说明
Katsoulidis, E., et al. 2005. Cancer Res.65, 9029.
Hayess, K., and Benndorf, R. 1997. Biochem. Pharmacol. 53, 1239.
Hayess, K., and Benndorf, R. 1997. Biochem. Pharmacol. 53, 1239.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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