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Merck
CN
所有图片(1)

文件

368059-M

Millipore

Granzyme B Substrate II, Fluorogenic

A fluorogenic substrate for the detection of granzyme B and caspase-8 activity.

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别名:
Granzyme B Substrate II, Fluorogenic, Z-IETD-AFC, Caspase-8 Substrate II
经验公式(希尔记法):
C37H42F3N5O13
分子量:
821.75
UNSPSC代码:
12352200

质量水平

检测方案

≥97% (HPLC)

形式

lyophilized solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

white

溶解性

DMSO: 1 mg/mL

荧光

λex ~400 nm
λem ~505 nm

储存温度

−20°C

一般描述

A fluorogenic substrate for the detection of granzyme B and caspase-8 activity. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
A fluorogenic substrate for the detection of granzyme B. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).

生化/生理作用

Primary Target
Fluorogenic substrate for the detection of granzyme B and caspase-8 activity

警告

Toxicity: Standard Handling (A)

序列

Z-Ile-Glu-Thr-Asp-AFC

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Karahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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