推荐产品
产品名称
Anti-β-Synuclein Antibody, clone Syn207, ascites fluid, clone Syn207, Upstate®
生物来源
mouse
质量水平
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
Syn207, monoclonal
种属反应性
rat, mouse, human
制造商/商品名称
Upstate®
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... SNCB(6620)
特异性
recombinant β-Synuclein
免疫原
full length recombinant human β-Synuclein
应用
Anti-β-Synuclein Antibody, clone Syn207 is an antibody against β-Synuclein for use in WB, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
质量
routinely evaluated by immunoblot lot detected β-Synuclein recombinant protein
目标描述
~17kDa
外形
Ascites
ascites with 0.05% sodium azide
储存及稳定性
2 years at -20°C
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
P H Tu et al.
Annals of neurology, 44(3), 415-422 (1998-09-28)
Recently, alpha-synuclein was shown to be a structural component of the filaments in Lewy bodies (LBs) of Parkinson's disease (PD), dementia with LBs (DLB) as well as the LB variant of Alzheimer's disease, and this suggests that alpha-synuclein could play
Emmy H Rannikko et al.
BMC neuroscience, 16, 57-57 (2015-09-09)
The pathological hallmarks of Parkinson's disease are intracellular inclusions composed mainly of misfolded α-synuclein (αSYN). Under physiological conditions αSYN is mostly localized in synapses. In addition, a portion of αSYN is secreted to the extracellular space, where it may be
Suna Lahut et al.
Disease models & mechanisms, 10(5), 619-631 (2017-01-22)
Parkinson's disease (PD) is a frequent neurodegenerative process in old age. Accumulation and aggregation of the lipid-binding SNARE complex component α-synuclein (SNCA) underlies this vulnerability and defines stages of disease progression. Determinants of SNCA levels and mechanisms of SNCA neurotoxicity
O Akil et al.
Journal of the Association for Research in Otolaryngology : JARO, 9(4), 452-463 (2008-07-31)
Synucleins are widely expressed synaptic proteins within the central nervous system that have been implicated in such neurodegenerative disorders as Parkinson's disease. In this study, an initial characterization of all three synucleins, alpha-, beta-, and gamma-synuclein, within the cochlea was
Alpha-synuclein: its biological function and role in neurodegenerative diseases.
Kaplan, Batia, et al.
Journal of Molecular Neuroscience, 20, 83-92 (2003)
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