36-008
Anti-α-Synuclein (SNCA) Antibody
UPSTATE®, mouse monoclonal, Syn211
别名:
Anti-NACP, Anti-PARK1, Anti-PARK4, Anti-PD1
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关于此项目
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
Syn211, monoclonal
Species reactivity:
human
Application:
IHC, IP, WB
Citations:
29
产品名称
抗α-突触核蛋白抗体，克隆Syn211, ascites fluid, clone Syn211, Upstate®
biological source
mouse
Quality Level
antibody form
ascites fluid
antibody product type
primary antibodies
clone
Syn211, monoclonal
species reactivity
human
packaging
antibody small pack of 25 μL
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
Gene Information
human ... SNCA(6622)
General description
~14.5kDa
Immunogen
全长重组人 α-突触核蛋白
Application
使用该抗 α-突触核蛋白抗体（克隆Syn211，经验证可用于 IP、WB、IH）检测 α-突触核蛋白。
研究子类别
神经退行性疾病
神经退行性疾病
研究类别
神经科学
神经科学
Biochem/physiol Actions
α-突触核蛋白
Physical form
腹水
Preparation Note
在 -20°C 条件下可保存 2 年
Analysis Note
通过免疫印迹对阿尔茨海默氏病患病的人全脑裂解液进行了常规评估。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Jay S Schneider et al.
Molecular and cellular neurosciences, 120, 103729-103729 (2022-04-22)
Among the pathological events associated with the dopaminergic neurodegeneration characteristic of Parkinson's disease (PD) are the accumulation of toxic forms of α-synuclein and microglial activation associated with neuroinflammation. Although numerous other processes may participate in the pathogenesis of PD, the
Sarah M O'Donovan et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 32(1), e13726-e13726 (2019-10-03)
A hallmark feature of Parkinson's disease (PD) is the build-up of α-synuclein protein aggregates throughout the brain; however α-synuclein is also expressed in enteric neurons. Gastrointestinal (GI) symptoms and pathology are frequently reported in PD, including constipation, increased intestinal permeability
Lien Veys et al.
Frontiers in aging neuroscience, 12, 614587-614587 (2021-02-02)
Although very different in etiology and symptoms, numerous neurodegenerative diseases can be classified as proteinopathies. More so, evidence indicates that the key misfolded proteins at the basis of different neuropathies might share common mechanisms of propagation. As such, the prion-like
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 36-008-25UL | 04054839337352 |