产品名称
Anti-Ganglioside GM2 Rabbit pAb, liquid, Calbiochem®
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
form
liquid
does not contain
preservative
species reactivity (predicted by homology)
all
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
dilution
(ELISA (1:200)
TLC Immunoblotting (1:100, colorimetric))
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Application
ELISA (1:200)
TLC Immunoblotting (1:100, colorimetric)
TLC Immunoblotting (1:100, colorimetric)
Disclaimer
Toxicity: Standard Handling (A)
General description
Anti-Ganglioside GM₂, rabbit polyclonal recognizes ganglioside GM₂ in a wide variety of species. It is validated for use in ELISA and TLC immunoblotting.
Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the GM2 ganglioside.
Recognizes ganglioside GM2.
Immunogen
purified, human ganglioside GM₂
Other Notes
Does not cross-react with other carbohydrate epitopes. Variables associated with assay conditions will dictate the optimal working dilution.
Yoshino, H., et al. 1993. J. Neurochem. 61, 658.
Kusunoki, S., et al. 1987. Neurology 37, 1795.
Kusunoki, S., et al. 1987. Neurology 37, 1795.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Yuehong Chen et al.
Journal of molecular medicine (Berlin, Germany), 96(12), 1359-1373 (2018-10-21)
Tay-Sachs disease (TSD) is a lethal lysosomal storage disease (LSD) caused by mutations in the HexA gene, which can lead to deficiency of β-hexosaminidase A (HexA) activity and consequent accumulation of its substrate, GM2 ganglioside. Recent reports that progranulin (PGRN)
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