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Merck
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安全信息

345749

Sigma-Aldrich

GDF-8 Propeptide

≥90% (SDS-PAGE), lyophilized powder, mouse

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.26

产品名称

GDF-8 Propeptide, His•Tag®, Mouse, Recombinant, GDF-8 Propeptide, His•Tag, Mouse, Recombinant, consists of amino acids 25-285, fused at the C-terminus to a His•Tag sequence, and expressed in NS0-derived mouse myeloma cells.

重组

expressed in mouse NSO cells (myeloma cells)

质量水平

100

方案

≥90% (SDS-PAGE)

表单

lyophilized

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

杂质

≤1.0 EU/μg protein Endotoxin

运输

ambient

储存温度

−20°C

一般描述

Recombinant, mouse growth differentiation factor-8 (GDF-8)/myostatin propeptide, consisting of amino acids 25-285, fused at the C-terminus to a His•Tag sequence, and expressed in NS0-derived mouse myeloma cells. GDF-8 is a secreted protein that is expressed during embryonic development and in adult skeletal muscle.

应用

GDF-8 Propeptide, His•Tag, Mouse, Recombinant, consists of amino acids 25-285, fused at the C-terminus to a His•Tag sequence, and expressed in NS0-derived mouse myeloma cells.

生化/生理作用

ED₅₀ = 0.05-0.25 µg/ml (using 40 ng/ml rmGDF-8) as measured by inhibition of rmGDF-8 activity in K562 human chronic myelogenous leukemia cells. Approximately 1 µg/ml will completely inhibit GDF-8 activity in K562 cells.

警告

Toxicity: Standard Handling (A)

外形

Lyophilized from 0.2 µm filtered PBS, BSA.

重悬

Following reconstituyion refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Reconstitute to 50 µg/ml with sterile PBS containing ≥1% human or bovine serum albumin.

其他说明

Hill, J.J. et al. 2003. Molecular Endocrinology17, 1144.
Thies, R.S. et al. 2001. Growth Factors18, 251.
Chang, H. et al. 2002. Endocrine Reviews23, 787.
McPherron, A.C. et al. 1997. Nature387, 83.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 2

法规信息

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