344935
Furin Substrate, Fluorogenic
A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 10⁴ s⁻¹M⁻¹).
别名:
Furin Substrate, Fluorogenic
产品名称
Furin Substrate, Fluorogenic, A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 10⁴ s⁻¹M⁻¹).
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
protect from light
color
white
solubility
water: 10 mg/mL
DMSO: soluble
fluorescence
λex 360 - 380 nm
λem 430-460 nm
shipped in
ambient
storage temp.
−20°C
Quality Level
Preparation Note
Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Lamango, N.S., et al. 1996. Arch. Biochem. Biophys.330, 238.
Hatsuzawa, K., et al. 1992. J. Biol. Chem. 267, 16094.
Hatsuzawa, K., et al. 1992. J. Biol. Chem. 267, 16094.
Pyr-Arg-Thr-Lys-Arg-AMC
Biochem/physiol Actions
Cell permeable: no
Primary Target
Fluorogenic substrate for furin
Fluorogenic substrate for furin
Product does not compete with ATP.
Reversible: no
kcat/Km ~ 2 x 104 s-1M-1 for furin
Disclaimer
Toxicity: Standard Handling (A)
General description
A fluorogenic substrate for furin (kcat/Km ~2 X 104 M-1 s-1), a mammalian homolog of the yeast Kex2 endoprotease. Also serves as a substrate for related protein, prohormone convertase 2 (PC2) (kcat/Km ~6 X 103 M-1 s-1). Excitation max: ~360-380 nm; emission max: ~430-460 nm).
A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 104 s-1M-1).
Physical form
Supplied as a trifluoroacetate salt.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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