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质量水平
方案
≥95% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
protect from light
颜色
white
溶解性
water: 10 mg/mL
DMSO: soluble
荧光
λex 360 - 380 nm
λem 430-460 nm
运输
ambient
储存温度
−20°C
一般描述
A fluorogenic substrate for furin (kcat/Km ~2 X 104 M-1 s-1), a mammalian homolog of the yeast Kex2 endoprotease. Also serves as a substrate for related protein, prohormone convertase 2 (PC2) (kcat/Km ~6 X 103 M-1 s-1). Excitation max: ~360-380 nm; emission max: ~430-460 nm).
A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 104 s-1M-1).
生化/生理作用
Cell permeable: no
Primary Target
Fluorogenic substrate for furin
Fluorogenic substrate for furin
Product does not compete with ATP.
Reversible: no
kcat/Km ~ 2 x 104 s-1M-1 for furin
警告
Toxicity: Standard Handling (A)
序列
Pyr-Arg-Thr-Lys-Arg-AMC
外形
Supplied as a trifluoroacetate salt.
重悬
Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Lamango, N.S., et al. 1996. Arch. Biochem. Biophys.330, 238.
Hatsuzawa, K., et al. 1992. J. Biol. Chem. 267, 16094.
Hatsuzawa, K., et al. 1992. J. Biol. Chem. 267, 16094.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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