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344911

Sigma-Aldrich

Fura-2 LR/AM

Acetoxymethyl (AM) derivative of FURA-PE3 with spectral properties similar to the parent compound.

别名:

Fura-2 LR/AM, Fura-2 Leakage Resistant (AM)

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About This Item

经验公式（希尔记法）:
C55H63N5O29
CAS号:
172890-84-5
分子量:
1258.10
MDL编号:
MFCD00285848
UNSPSC代码:
12171500
NACRES:
NA.25

质量水平

100

方案

≥95% (HPLC)

表单

gum

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

light yellow

溶解性

DMSO: 10 mg/mL

荧光

λex 368 nm (low)
λex 374 nm (high)
λem 518 nm (low)
λem 524 nm (high)

运输

ambient

储存温度

−20°C

SMILES字符串

N1(CCN(CC1)C(=O)CCc2cc(c(cc2)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOc3cc4c([o]c(c4)c5ncc([o]5)C(=O)OCOC(=O)C)cc3N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

InChI

1S/C55H63N5O29/c1-33(61)76-27-82-49(68)22-57-11-13-58(14-12-57)48(67)10-8-39-7-9-41(59(23-50(69)83-28-77-34(2)62)24-51(70)84-29-78-35(3)63)44(17-39)74-15-16-75-45-18-40-19-46(54-56-21-47(89-54)55(73)87-32-81-38(6)66)88-43(40)20-42(45)60(25-52(71)85-30-79-36(4)64)26-53(72)86-31-80-37(5)65/h7,9,17-21H,8,10-16,22-32H2,1-6H3

InChI key

CGAZNAYDEAJZHQ-UHFFFAOYSA-N

一般描述

Acetoxymethyl (AM) derivative of FURA-PE3 with spectral properties similar to the parent compound. Can be loaded into cells in a manner similar to FURA 2/AM. Hydrolysis by non-specific esterases traps the indicator in the cytosol. Compared to FURA-2, it is retained longer in the cell. Note: 1 set = 10 x 50 µg.
An acetoxymethyl (AM) derivative of FURA-PE3. with spectral properties similar to the parent compound. Can be loaded into cells in a manner similar to FURA 2/AM (Cat. No. 344905). Hydrolysis by non-specific esterases traps the indicator in the cytosol. Spectral properties in the presence of low calcium concentrations (ex. 364 nm, em. 508 nm) differ from those during high calcium conditions (ex. 335 nm, em. 495 nm). Note: 1 set = 10 x 50 µg.

生化/生理作用

Cell permeable: no
Primary Target
Calcium Probes
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

其他说明

Abe, F., et al. 1995. Br. J. Pharmacol.116, 3000.
Vorndran, C., et al. 1995. Biophys. J.69, 2114.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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