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产品名称
5-氟尿嘧啶, Potent antitumor agent.
描述
Merck USA index - 14, 4181
质量水平
方案
≥98% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
white
溶解性
hot water: 1 mg/mL
methanol: 1 mg/mL
DMF: 5 mg/mL
DMSO: 5 mg/mL
运输
ambient
储存温度
2-8°C
SMILES字符串
Fc1[c]([nH][c]([nH]c1)=O)=O
InChI
1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChI key
GHASVSINZRGABV-UHFFFAOYSA-N
一般描述
一种抑制氨基异丁酸-丙酮酸氨基转移酶的强效抗肿瘤药。诱导人结肠癌细胞系的凋亡。
强效抗肿瘤药。抑制氨基异丁酸-丙酮酸氨基转移酶。诱导人结肠癌细胞系的凋亡。
生化/生理作用
主要靶标
氨基异丁酸-丙酮酸氨基转移酶
氨基异丁酸-丙酮酸氨基转移酶
产物不与ATP竞争。
可逆：否
细胞渗透性：否
警告
毒性：有害（C）
重悬
复溶后，等分并冷冻保存（-20°C）。储备溶液在-20°C下可稳定保存至多3个月。
其他说明
Pressacco, J., et al. 1996.Br. J. Cancer72, 939.
Shchepotin, I.B., et al. 1994.Anticancer Res.14, 1027.
Shchepotin, I.B., et al. 1994.Anticancer Res.14, 1027.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Carc. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
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