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343922

5-氟尿嘧啶

≥98% (HPLC), solid, thymidylate synthase inhibitor, Calbiochem®

别名:

5-氟尿嘧啶

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关于此项目

经验公式（希尔记法）:
C4H3FN2O2
化学文摘社编号:
51-21-8
分子量:
130.08
UNSPSC Code:
12171500
NACRES:
NA.77
MDL number:
MFCD00006018
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze
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产品名称

5-氟尿嘧啶, Potent antitumor agent.

description

Merck USA index - 14, 4181

Quality Level

100

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

hot water: 1 mg/mL, methanol: 1 mg/mL, DMF: 5 mg/mL, DMSO: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

Fc1[c]([nH][c]([nH]c1)=O)=O

InChI

1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)

InChI key

GHASVSINZRGABV-UHFFFAOYSA-N

General description

一种抑制氨基异丁酸-丙酮酸氨基转移酶的强效抗肿瘤药。诱导人结肠癌细胞系的凋亡。
强效抗肿瘤药。抑制氨基异丁酸-丙酮酸氨基转移酶。诱导人结肠癌细胞系的凋亡。

Biochem/physiol Actions

主要靶标
氨基异丁酸-丙酮酸氨基转移酶
产物不与ATP竞争。
可逆：否
细胞渗透性：否

Preparation Note

复溶后，等分并冷冻保存（-20°C）。储备溶液在-20°C下可稳定保存至多3个月。

Other Notes

Pressacco, J., et al. 1996.Br. J. Cancer72, 939.
Shchepotin, I.B., et al. 1994.Anticancer Res.14, 1027.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

毒性：有害（C）

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

hcodes

H301,H351

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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货号GTIN
343922-1GM04055977195132