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Merck
CN
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文件

324900

Sigma-Aldrich

L-(–)-Epinephrine-(+)-bitartrate

α,β-Adrenergic receptor agonist.

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别名:
L-(–)-Epinephrine-(+)-bitartrate, 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanol, Adrenaline Bitartrate
经验公式（希尔记法）:
C9H13NO3 · xC4H6O6
CAS号:
51-42-3
分子量:
183.20 (free base basis)
MDL编号:
MFCD00035077
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

100

检测方案

≥95% (TLC)

形式

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)

颜色

white

溶解性

ethanol: soluble
water: soluble

运输

ambient

储存温度

2-8°C

InChI

1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1

InChI key

YLXIPWWIOISBDD-NDAAPVSOSA-N

一般描述

α,β-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP.
An α,β-adrenergic receptor agonist. Has positive chronotropic and inotropic effects on cardiac muscle. Its major actions are mediated via activation of adenylate cyclase. Enhances mitochondrial oxidation of substrates.

生化/生理作用

Cell permeable: no
Primary Target
α,β-Adrenergic receptor agonist
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

重悬

Unstable in solution; reconstitute just prior to use.

其他说明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Oudit, G.Y., and Butler, D.G. 1995. Am. J. Physiol.268, R1273.
Mohan, C., et al. 1991. Arch. Biochem. Biophys.287, 18.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H300

危险分类

Acute Tox. 1 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Hiroki Yano et al.
Scientific reports, 13(1), 7707-7707 (2023-05-13)
Clinical scenario 1 (CS1) is acute heart failure (HF) characterized by transient systolic blood pressure (SBP) elevation and pulmonary congestion. Although it is managed by vasodilators, the molecular mechanism remains unclear. The sympathetic nervous system plays a key role in

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