324900
L-(–)-Epinephrine-(+)-bitartrate
α,β-Adrenergic receptor agonist.
别名:
L-(–)-Epinephrine-(+)-bitartrate, 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanol, Adrenaline Bitartrate
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所有图片(1)
About This Item
经验公式（希尔记法）:
C9H13NO3 · xC4H6O6
CAS号:
分子量:
183.20 (free base basis)
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77
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质量水平
方案
≥95% (TLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
颜色
white
溶解性
ethanol: soluble
water: soluble
运输
ambient
储存温度
2-8°C
SMILES字符串
N(C[C@H](O)c1cc(c(cc1)O)O)C.O[C@H]([C@@H](O)C(=O)O)C(=O)O
InChI
1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
InChI key
YLXIPWWIOISBDD-NDAAPVSOSA-N
一般描述
α,β-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP.
An α,β-adrenergic receptor agonist. Has positive chronotropic and inotropic effects on cardiac muscle. Its major actions are mediated via activation of adenylate cyclase. Enhances mitochondrial oxidation of substrates.
生化/生理作用
Cell permeable: no
Primary Target
α,β-Adrenergic receptor agonist
α,β-Adrenergic receptor agonist
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)
重悬
Unstable in solution; reconstitute just prior to use.
其他说明
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Oudit, G.Y., and Butler, D.G. 1995. Am. J. Physiol.268, R1273.
Mohan, C., et al. 1991. Arch. Biochem. Biophys.287, 18.
Mohan, C., et al. 1991. Arch. Biochem. Biophys.287, 18.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险声明
危险分类
Acute Tox. 1 Oral
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Hiroki Yano et al.
Scientific reports, 13(1), 7707-7707 (2023-05-13)
Clinical scenario 1 (CS1) is acute heart failure (HF) characterized by transient systolic blood pressure (SBP) elevation and pulmonary congestion. Although it is managed by vasodilators, the molecular mechanism remains unclear. The sympathetic nervous system plays a key role in
Joshua Kranrod et al.
The Journal of biological chemistry, 300(6), 107372-107372 (2024-05-17)
OMT-28 is a metabolically robust small molecule developed to mimic the structure and function of omega-3 epoxyeicosanoids. However, it remained unknown to what extent OMT-28 also shares the cardioprotective and anti-inflammatory properties of its natural counterparts. To address this question
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