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描述
Merck USA index - 14, 3517
质量水平
表单
solution
反应适用性
reagent type: chelator
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
浓度
500 mM
颜色
colorless to pale yellow
pH值（酸碱度）
8
运输
ambient
储存温度
10-30°C
SMILES字符串
N(CCN(CC(=O)O)CC(=O)O)(CC(=O)O)CC(=O)O
InChI
1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
InChI key
KCXVZYZYPLLWCC-UHFFFAOYSA-N
一般描述
乙二胺四乙酸(EDTA)是一种金属螯合剂，用于治疗铅或汞等重金属中毒患者。它还用于减少酶免疫测定中的非特异性血清蛋白相互作用。凭借抑制蛋白凝集的能力，它可用于制作血液/血浆样品并在免疫分析中检测CD3细胞。EDTA与缓冲液或离子盐结合，刺激血液样本中的免疫细胞。它在治疗和分析牛皮癣方面有多方面的应用。EDTA作为抗氧化剂可以对抗银屑病，同时它也用于在分子水平上研究这种疾病。
用于放射免疫成像的有用试剂。
应用
EDTA, 500 mM溶液，pH 8.0，ULTROL®级，与磷酸盐缓冲盐水(PBS)一起用于细胞破坏，以收获线虫的隐窝原位杂交。它也用作等电聚焦溶液(IEF)的组分，以重悬肌原纤维并进行蛋白质研究。
警告
毒性：刺激性（B）
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
M P Richards et al.
Journal of chromatography, 402, 243-256 (1987-07-31)
Reversed-phase high-performance liquid chromatography (RP-HPLC) was used to isolate, characterize and quantitate liver and kidney metallothionein (MT) isoforms from a variety of animal species. The isoMTs were eluted from a radially compressed C18 column with a neutral sodium phosphate buffer
Amreen Sunil et al.
Cureus, 13(7), e16424-e16424 (2021-07-20)
Psoriasis is a long-term, autoimmune inflammatory condition characterized by red, scaly plaques that can range from a few patches to total skin coverage. Over the past 60 years, and more recently, the metal-chelating agent ethylenediaminetetraacetic acid (EDTA) has proven increasingly
Krishnan MohanKumar et al.
American journal of physiology. Gastrointestinal and liver physiology, 318(4), G705-G716 (2020-02-25)
Anemia is a frequent diagnosis in critically ill infants, but the clinical implications of severe anemia in these patients remain unclear. In this study, we examined preweaned mice to investigate the effects of severe anemia during early infancy on gut
Walter E Knight et al.
STAR protocols, 2(4), 100912-100912 (2021-11-11)
When cultured under typical conditions, human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are structurally and functionally immature. We have previously demonstrated that culture of hiPSC-CMs in maturation medium containing fatty acids, in combination with culture on micropatterned surfaces, produces cells that
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