324413
Dynamin Inhibitor IV, Hydroxy-Dynasore
The Dynamin Inhibitor IV, Hydroxy-Dynasore controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Cell Signaling applications.
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别名:
Dynamin Inhibitor IV, Hydroxy-Dynasore, 3-Hydroxynaphthalene-2-carboxylic acid-(2,4,5-trihydroxybenzylidene)-hydrazide
经验公式（希尔记法）:
C18H14N2O5
分子量:
338.31
UNSPSC代码:
12352200
NACRES:
NA.77
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质量水平
检测方案
≥97% (HPLC)
形式
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
yellow
溶解性
DMSO: 100 mg/mL
运输
ambient
储存温度
2-8°C
一般描述
A highly potent (IC50 = 0.38 and 2.6 µM for dynamin I and dynamin II, respectively), cell-permeable and in vivo bioavailable (30 mg/kg in mice, i.p.) hydroxylated analog of Dynamin Inhibitor I, Dynasore (Cat. No. 324410).
A highly potent (IC50 = 0.38 and 2.6 µM for dynamin I and dynamin II, respectively), cell-permeable and in vivo bioavailable (30 mg/kg in mice, i.p.) hydroxylated analog of Dynamin Inhibitor I, Dynasore (Cat. No. 324410).
包装
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
其他说明
Harper, C.B., et al. 2011. J. Biol. Chem.286, 35966.
Howes, M.T., et al. 2010. J. Cell Biol.190, 675.
Howes, M.T., et al. 2010. J. Cell Biol.190, 675.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Enikő Pergel et al.
International journal of molecular sciences, 22(19) (2021-10-14)
TMEM175 (transmembrane protein 175) coding sequence variants are associated with increased risk of Parkinson's disease. TMEM175 is the ubiquitous lysosomal K+ channel regulated by growth factor receptor signaling and direct interaction with protein kinase B (PKB/Akt). In the present study
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