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Merck
CN
所有图片(1)

主要文件

317505

Sigma-Aldrich

1,2-二辛基- sn- 甘油-CAS 60514-48-9-Calbiochem

Cell-permeable activator of protein kinase C (PKC).

别名:

1,2-Dioctanoyl-sn-glycerol, DOG, PKC Activator IV

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About This Item

经验公式(希尔记法):
C19H36O5
CAS号:
分子量:
344.49
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

表单

oil

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

clear colorless

溶解性

chloroform: soluble
ethyl acetate: soluble

运输

wet ice

储存温度

−70°C

SMILES字符串

O([C@H](COC(=O)CCCCCCC)CO)C(=O)CCCCCCC

InChI

1S/C19H36O5/c1-3-5-7-9-11-13-18(21)23-16-17(15-20)24-19(22)14-12-10-8-6-4-2/h17,20H,3-16H2,1-2H3/t17-/m0/s1

InChI key

ZQBULZYTDGUSSK-KRWDZBQOSA-N

一般描述

Cell-permeable activator of protein kinase C (PKC). Exhibits lower affinity for PKCα than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.
Cell-permeable activator of protein kinase C; however, it has lower affinity for PKCa than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.

生化/生理作用

Cell permeable: yes
Primary Target
Protein kinase C
Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Unstable in solution; reconstitute just prior to use.

分析说明

Single spot by TLC

其他说明

Ferro, T.J., et al. 1993. Am. J. Physiol. 264, L7.
MacEwan, D.J., et al. 1993. Eur. J. Pharmacol. 246, 9.
Davis, R.J. 1985. J. Biol. Chem.260, 1562.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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