317505
1,2-二辛基- sn- 甘油-CAS 60514-48-9-Calbiochem
Cell-permeable activator of protein kinase C (PKC).
别名:
1,2-Dioctanoyl-sn-glycerol, DOG, PKC Activator IV
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关于此项目
经验公式（希尔记法）:
C19H36O5
化学文摘社编号:
分子量:
344.49
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
产品名称
1,2-二辛基- sn- 甘油-CAS 60514-48-9-Calbiochem, Cell-permeable activator of protein kinase C (PKC).
SMILES string
O([C@H](COC(=O)CCCCCCC)CO)C(=O)CCCCCCC
InChI
1S/C19H36O5/c1-3-5-7-9-11-13-18(21)23-16-17(15-20)24-19(22)14-12-10-8-6-4-2/h17,20H,3-16H2,1-2H3/t17-/m0/s1
InChI key
ZQBULZYTDGUSSK-KRWDZBQOSA-N
description
RTECS - RH0764500
form
oil
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
clear colorless
solubility
chloroform: soluble
ethyl acetate: soluble
shipped in
wet ice
storage temp.
−70°C
Quality Level
Analysis Note
Single spot by TLC
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Protein kinase C
Protein kinase C
Reversible: no
Disclaimer
Toxicity: Standard Handling (A)
General description
Cell-permeable activator of protein kinase C (PKC). Exhibits lower affinity for PKCα than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.
Other Notes
Ferro, T.J., et al. 1993. Am. J. Physiol. 264, L7.
MacEwan, D.J., et al. 1993. Eur. J. Pharmacol. 246, 9.
Davis, R.J. 1985. J. Biol. Chem.260, 1562.
MacEwan, D.J., et al. 1993. Eur. J. Pharmacol. 246, 9.
Davis, R.J. 1985. J. Biol. Chem.260, 1562.
Packaging
Packaged under inert gas
Preparation Note
Unstable in solution; reconstitute just prior to use.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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