309825
Dihydrorhodamine 123
Cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite.
别名:
Dihydrorhodamine 123
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关于此项目
经验公式（希尔记法）:
C21H18N2O3
化学文摘社编号:
分子量:
346.38
UNSPSC Code:
12352116
NACRES:
NA.21
MDL number:
产品名称
Dihydrorhodamine 123, Cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite.
SMILES string
Nc1cc2c(cc1)C(c4c(cc(cc4)N)O2)c3c(cccc3)C(=O)OC
InChI
1S/C21H18N2O3/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20/h2-11,20H,22-23H2,1H3
InChI key
FNEZBBILNYNQGC-UHFFFAOYSA-N
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
pink-white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
Cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite. Dihydrorhodamine is not fluorescent unless it is converted to rhodamine 123.
Biochem/physiol Actions
Product does not compete with ATP.
Reversible: no
Cell permeable: yes
Primary Target
Detection of reactive oxygen species (ROS)
Detection of reactive oxygen species (ROS)
Disclaimer
Toxicity: Standard Handling (A)
Other Notes
Crow, J.P. 1997. Nitric Oxide1, 145.
Kim, Y.M., et al. 1996. Infect Immun. 64, 3074.
Williams, M.S., and Henkart, P.A. 1996. J. Immunol. 157, 2395.
van de Water, B., et al. 1995. Mol. Pharmacol. 48, 928.
Royall, J.A., and Ischiropoulos, H. 1993. Arch. Biochem. Biophys. 302, 348.
Kim, Y.M., et al. 1996. Infect Immun. 64, 3074.
Williams, M.S., and Henkart, P.A. 1996. J. Immunol. 157, 2395.
van de Water, B., et al. 1995. Mol. Pharmacol. 48, 928.
Royall, J.A., and Ischiropoulos, H. 1993. Arch. Biochem. Biophys. 302, 348.
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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