跳转至内容
Merck
CN
所有图片(1)

文件

264150

Sigma-Aldrich

Caspase-3 Substrate IV, Fluorogenic

Fluorogenic caspase-3 substrate.

登录查看公司和协议定价
所有图片(1)
别名:
Caspase-3 Substrate IV, Fluorogenic, Z-DEVD-AFC
经验公式（希尔记法）:
C36H38F3N5O14
CAS号:
1177935-21-5
分子量:
821.71
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

100

检测方案

≥95% (HPLC)

形式

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

white to off-white

溶解性

DMSO: 10 mg/mL

荧光

λex ~400 nm
λem ~505 nm

运输

ambient

储存温度

−20°C

一般描述

Fluorogenic CPP-32/apopain substrate. Also acts as a substrate for granzyme B-processed ICE-LAP3. Reaction can be monitored by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. Excitation max: ~400 nm; emission max: ~505 nm.
Fluorogenic caspase-3 substrate. Also acts as a substrate for granzyme B-processed ICE-LAP3. Reaction can be monitored by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. Also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10.

生化/生理作用

Cell permeable: no
Primary Target
Fluorogenic caspase-3 substrate.
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Standard Handling (A)

序列

Z-Asp-Glu-Val-Asp-AFC

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C.

其他说明

Keramaris, E., et al. 2000. Mol. Cell Neurosci. 15, 368.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Kluck, R.M., et al. 1997. Science275, 1132.
Talanian, J., et al. 1997. J. Biol. Chem.272, 9677.
Chinnaiyan, A.M., et al. 1996. Curr. Biol.6, 897.
Nicholson, D.W., et al. 1995. Nature376, 37.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门