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产品名称
细胞松弛素D,来源于Zygosporium mansonii, Cytochalasin D, Zygosporium mansonii, CAS 22144-77-0, is a fungal toxin that is about 10-fold more potent than cytochalasin B in inhibiting actin filament function. Blocks cytoplasmic division.
SMILES string
N1[C@H]([C@H]3[C@]4([C@H]([C@@H](C(=C)[C@H]3C)O)\C=C\C[C@@H](C(=O)[C@@](\C=C\[C@H]4OC(=O)C)(O)C)C)C1=O)Cc2ccccc2
InChI
1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
InChI key
SDZRWUKZFQQKKV-JHADDHBZSA-N
description
Merck USA index - 14, 2790
assay
≥98% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
white
solubility
DMSO: 2 mg/mL
chloroform: 2 mg/mL
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
肌动蛋白丝功能
Disclaimer
General description
Other Notes
Blankson, H., et al. 1995.Exp.Cell Res.218, 522.
Melamed, I., et al. 1995.Biochem.Biophys.Res. Commun.209, 1102.
Verschueren, H., et al. 1995.Eur. J. Cell Biol.66, 335.
Aszalos, A., et al. 1994.Cell Immunol. 157, 81.
Wang, W.H., et al. 1994.Am. J. Physiol.267, F592.
Betina, V., and Micekova, D. 1972.Chem. Abstr.77, 160508q.
Katagiri, K., and Matsuura, S. 1971.J. Antibiot.24, 722.
Preparation Note
Legal Information
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
法规信息
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