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质量水平
描述
Merck USA index - 14, 2603
表单
liquid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
溶解性
water: soluble
运输
wet ice
储存温度
2-8°C
一般描述
M.W. 23,000 (monomer); 115,000 (pentamer).
Native C-reactive protein from human ascites. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer.
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
外形
In 150 mM NaCl, 20 mM Tris, 2 mM CaCl₂, 0.1% NaN₃, pH 7.5.
制备说明
Prepared from ascites that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
分析说明
Single band by SDS-PAGE
其他说明
Christner, R.B., and Mortensen, R.F. 1994. J. Biol. Chem. 269, 9760.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Katrine Pilely et al.
Frontiers in immunology, 8, 1040-1040 (2017-09-14)
Inflammation is a part of the initial process leading to atherosclerosis and cholesterol crystals (CC), found in atherosclerotic plaques, which are known to induce complement activation. The pentraxins C-reactive protein (CRP), long pentraxin 3 (PTX3), and serum amyloid P component
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