C-Reactive Protein, Human Ascites

Name: C-Reactive Protein, Human Ascites
Brand: MM

C - reactive protein, Human Ascites, CAS 9007-41-4, is a major acute-phase plasma protein that composed of five identical non-covalently linked subunits.

别名:

C-Reactive Protein, Human Ascites, CRP

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关于此项目

化学文摘社编号:

9007-41-4

UNSPSC Code:

12352202

NACRES:

NA.25

MDL number:

MFCD00130690

主要文件

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产品名称

C-Reactive Protein, Human Ascites, C - reactive protein, Human Ascites, CAS 9007-41-4, is a major acute-phase plasma protein that composed of five identical non-covalently linked subunits.

form

liquid

description

Merck USA index - 14, 2603

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

solubility

water: soluble

shipped in

wet ice

storage temp.

2-8°C

Quality Level

100

Other Notes

Christner, R.B., and Mortensen, R.F. 1994. J. Biol. Chem. 269, 9760.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 150 mM NaCl, 20 mM Tris, 2 mM CaCl₂, 0.1% NaN₃, pH 7.5.

Preparation Note

Prepared from ascites that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Analysis Note

Single band by SDS-PAGE

Disclaimer

Toxicity: Standard Handling (A)

General description

M.W. 23,000 (monomer); 115,000 (pentamer).

Native C-reactive protein from human ascites. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca²⁺-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer.

wgk

WGK 2

存储类别

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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C-Reactive Protein Binds to Cholesterol Crystals and Co-Localizes with the Terminal Complement Complex in Human Atherosclerotic Plaques.

Katrine Pilely et al.

Frontiers in immunology, 8, 1040-1040 (2017-09-14)

Inflammation is a part of the initial process leading to atherosclerosis and cholesterol crystals (CC), found in atherosclerotic plaques, which are known to induce complement activation. The pentraxins C-reactive protein (CRP), long pentraxin 3 (PTX3), and serum amyloid P component

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C-Reactive Protein, Human Ascites