219445
Cdk2 Inhibitor II
The Cdk2 Inhibitor II, also referenced under CAS 222035-13-4, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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别名:
Cdk2 Inhibitor II, Compound 3
经验公式（希尔记法）:
C14H11BrN4O3S
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质量水平
检测方案
≥95% (sum of two isomers, HPLC)
形式
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
yellow
溶解性
DMSO: 5 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A cell-permeable, reversible, ATP-competitive, potent and selective inhibitor of Cdk2 (IC50 = 60 nM).
生化/生理作用
Cell permeable: yes
Primary Target
CDK2
CDK2
Product competes with ATP.
Reversible: yes
Target IC50: 60 nM against Cdk2
包装
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Davis, S.T., et al. 2001. Science291, 134.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, et al.
Molecular Cell, 82, 3350-3365 (2022)
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