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文件

219399

Cathepsin D Substrate I

Name: Cathepsin D Substrate I
Brand: MM

Useful as a substrate for the determination of cathepsin D activity.

别名:

Cathepsin D Substrate I, Bz-RGFFP-4-MeOβNA, HCl

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About This Item

经验公式（希尔记法）:

C₄₉H₅₅N₉O₇ · xHCl

分子量:

882.02 (free base basis)

UNSPSC代码:

51111800

NACRES:

NA.77

质量水平

100

检测方案

≥95% (HPLC)

形式

lyophilized solid

制造商/商品名称

Calbiochem^®

储存条件

OK to freeze
desiccated
protect from light

颜色

white

溶解性

DMSO: 5 mg/mL

荧光

λ_ex ~345 nm
λ_em ~425 nm

运输

ambient

储存温度

−20°C

一般描述

A useful substrate for colorimetric or fluorometric assay of cathepsin D activity. Cathepsin D hydrolyzes the Phe-Phe bond. Dipeptidyl aminopeptidase II is required to free the 4-methoxy-β-naphthylamine (4MβNA). Excitation max: ~345 nm; emission max: ~425 nm.

Useful as a substrate for the determination of cathepsin D activity. Suitable for either colorimetric or fluorometric assay. Cathepsin D hydrolyzes the Phe-Phe bond. Requires dipeptidyl aminopeptidase II to free 4-methoxy-β-naphthylamine (4MeOβNA).

生化/生理作用

Cell permeable: no

Primary Target
Substrate for the determination of cathepsin D activity

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

序列

Bz-Arg-Gly-Phe-Phe-Pro-4MeOβNA, HCl

其他说明

Takahashi, T., and Tang, J. 1981. Methods Enzymol.80, 565.
Smith, R.E., and Van Frank, R.M. 1975. in Lysosomes in Biology and Pathology4 (Dingle, J.T., and Dean, R.T., eds.) p. 193, American Elsevier, Holland.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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