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Merck
CN

219007

半胱天冬酶抑制剂VI

Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.

别名:

半胱天冬酶抑制剂VI, Z-VAD-FMK

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关于此项目

经验公式(希尔记法):
C21H28FN3O7
化学文摘社编号:
分子量:
453.46
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.54
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产品名称

半胱天冬酶抑制剂VI, Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.

form

solid

SMILES string

FCC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C)CC(=O)O

InChI

1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1

InChI key

SUUHZYLYARUNIA-YEWWUXTCSA-N

assay

≥98% (HPLC)

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated

color

off-white

solubility

DMSO: 9 mg/mL

shipped in

ambient

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

产物不与ATP竞争。
可逆:否
细胞渗透性:否

Disclaimer

毒性:标准处理(A)

General description

不可逆的一般半胱天冬酶抑制剂。可用于涉及重组、分离和纯化的半胱天冬酶的研究。与半胱天冬酶抑制剂I(目录编号627610)不同,该抑制剂不需要用酯酶进行预处理即可进行体外研究。也可获得10 mM(1 mg/221 µl)半胱天冬酶抑制剂VI的DMSO溶液(目录号219011)。

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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