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Merck
CN
所有图片(1)

主要文件

218829

Sigma-Aldrich

Caspase-3 Substrate IX, Fluorogenic

A non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide that acts as a highly sensitive, photostable caspase-3 fluorogenic substrate.

别名:

Caspase-3 Substrate IX, Fluorogenic, (Z-DEVD)₂-Rh 110

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About This Item

经验公式(希尔记法):
C72H78N10O27
分子量:
1515.44
UNSPSC代码:
12352200

质量水平

方案

≥95% (HPLC)

表单

lyophilized solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated
protect from light

颜色

yellow

溶解性

DMSO: 1 mg/mL

荧光

λex ~485 nm
λem ~535 nm

运输

wet ice

储存温度

−20°C

一般描述

A non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide that acts as a highly sensitive, photo-stable caspase-3 fluorogenic substrate. Reported to detect less than 1 ng/ml of caspase-3. Also reported to detect capase-3 activity in intact cells by flow cytometry. Useful for high throughput screening applications. Excitation max: ~485 nm; emission max: ~535 nm.
A non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide that acts as a highly sensitive, photostable caspase-3 fluorogenic substrate. Reported to detect less than 1 ng/ml of caspase-3. Useful for high throughput screening applications.

生化/生理作用

Cell permeable: no
Primary Target
A highly sensitive, photostable caspase-3 fluorogenic substrate
Product does not compete with ATP.
Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

序列

(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110

外形

Supplied as a trifluoroacetate salt.

重悬

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Hug, H., et al. 1999. Biochemistry38, 13906.
Liu, J., et al. 1999. Bioorg. Med. Chem. Lett.9, 3231.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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